Gastrin anticorps
Aperçu rapide pour Gastrin anticorps (ABIN115354)
Antigène
Voir toutes Gastrin (GAST) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
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The antibody is specific against gastrin-containing cells. This antibody reacts with human gastrin I and human gastrin I fragments.
Cellular Localization: Cytoplasmic -
Purification
- Purified
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Immunogène
- Recombinant Gastrin conjugated to KLH.
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Indications d'application
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Immunohistochemistry on formalin-fixed paraffin embedded sections: diluted of 1: 50-1: 100 in an ABC method (30 minutes at room temperature)Recommended Positive Control: Stomach
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- containing sodium azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Gastrin (GAST)
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Autre désignation
- Gastrin
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Sujet
- Gastrin is mainly known by its first described role as a gastric acid-hormone but the protein also has the ability to promote cellular growth. More recently, gastrin has been suggested to induce leukocyte-endothelial cell interactions and to have a pro-inflammatory effect. Gastrin has two biologically active peptide forms, G34 and G17 and they activate two different receptors: the CCK-1 receptor, which has low affinity for gastrin but high affinity for the related hormone cholecystokinin (CCK), and the CCK-2 receptor, which has high affinity for both gastrin and CCK and mediates the acid-secretory as well as the proliferative effects of gastrin.Synonyms: GAS, GAST
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ID gène
- 2520
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NCBI Accession
- NP_000796
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UniProt
- P01350
Antigène
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